MOTS-c Dosage Chart and Protocol Guide
MOTS-c is a mitochondrial-derived peptide studied for its role in metabolism and energy regulation. It is a newer research target, and dosing draws on early studies and community protocols. This guide collects the reported ranges. Figures are research-reported, not dosing advice.
How MOTS-c dosing is structured
MOTS-c doses are given in milligrams and are usually spread across the week rather than taken daily. Because it is studied for metabolic signaling rather than acute effects, protocols favor a steady rhythm over frequent dosing.
| Context | Reported dose | Frequency |
|---|---|---|
| Lower research range | 5 mg | 2 to 3 times per week |
| Common research range | 10 mg | 2 to 3 times per week |
| Cycle length | 4 to 6 weeks | then a break |
A frequent pattern is 10 mg two or three times weekly for a set block. Convert a milligram dose into syringe units with the dosage calculator using your vial size and water amount.
Timing and lifestyle context
MOTS-c research links it to exercise metabolism, so some protocols place doses around training. Review tolerability in the MOTS-c side effects overview and what people report over time in MOTS-c before and after.
Sourcing
As a newer peptide, quality varies more between suppliers. Third-party tested material matters. Compare vendors on the supplier list before starting a research block.